![In Vivo SiRNA Transfection and Gene Knockdown in Spinal Cord via Rapid Noninvasive Lumbar Intrathecal Injections in Mice | Protocol In Vivo SiRNA Transfection and Gene Knockdown in Spinal Cord via Rapid Noninvasive Lumbar Intrathecal Injections in Mice | Protocol](https://cloudfront.jove.com/files/ftp_upload/51229/51229fig1.jpg)
In Vivo SiRNA Transfection and Gene Knockdown in Spinal Cord via Rapid Noninvasive Lumbar Intrathecal Injections in Mice | Protocol
![Comparative in Vivo Investigation of Intrathecal and Intracerebroventricular Administration with Melanocortin Ligands MTII and AGRP into Mice. - Abstract - Europe PMC Comparative in Vivo Investigation of Intrathecal and Intracerebroventricular Administration with Melanocortin Ligands MTII and AGRP into Mice. - Abstract - Europe PMC](https://europepmc.org/articles/PMC5821609/bin/nihms923547u1.jpg)
Comparative in Vivo Investigation of Intrathecal and Intracerebroventricular Administration with Melanocortin Ligands MTII and AGRP into Mice. - Abstract - Europe PMC
Biodistribution of Adeno-Associated Virus Serotype 5 Viral Vectors Following Intrathecal Injection | Molecular Pharmaceutics
![A Method for in Vivo Quantification Of Cytokine IL-1β In The Rat Intrathecal Space | ACS Applied Bio Materials A Method for in Vivo Quantification Of Cytokine IL-1β In The Rat Intrathecal Space | ACS Applied Bio Materials](https://pubs.acs.org/cms/10.1021/acsabm.9b00958/asset/images/large/mt9b00958_0007.jpeg)
A Method for in Vivo Quantification Of Cytokine IL-1β In The Rat Intrathecal Space | ACS Applied Bio Materials
![Schematic diagram of mouse skeleton showing the site of intrathecal... | Download Scientific Diagram Schematic diagram of mouse skeleton showing the site of intrathecal... | Download Scientific Diagram](https://www.researchgate.net/publication/326384767/figure/fig35/AS:661804241932288@1534797835144/Schematic-diagram-of-mouse-skeleton-showing-the-site-of-intrathecal-injection-at-the.png)
Schematic diagram of mouse skeleton showing the site of intrathecal... | Download Scientific Diagram
![Frontiers | Comparative Effectiveness of Intracerebroventricular, Intrathecal, and Intranasal Routes of AAV9 Vector Administration for Genetic Therapy of Neurologic Disease in Murine Mucopolysaccharidosis Type I Frontiers | Comparative Effectiveness of Intracerebroventricular, Intrathecal, and Intranasal Routes of AAV9 Vector Administration for Genetic Therapy of Neurologic Disease in Murine Mucopolysaccharidosis Type I](https://www.frontiersin.org/files/Articles/618360/fnmol-14-618360-HTML-r1/image_m/fnmol-14-618360-g001.jpg)
Frontiers | Comparative Effectiveness of Intracerebroventricular, Intrathecal, and Intranasal Routes of AAV9 Vector Administration for Genetic Therapy of Neurologic Disease in Murine Mucopolysaccharidosis Type I
![IJMS | Free Full-Text | Intrathecal Injection in a Rat Model: A Potential Route to Deliver Human Wharton's Jelly-Derived Mesenchymal Stem Cells into the Brain IJMS | Free Full-Text | Intrathecal Injection in a Rat Model: A Potential Route to Deliver Human Wharton's Jelly-Derived Mesenchymal Stem Cells into the Brain](https://www.mdpi.com/ijms/ijms-21-01272/article_deploy/html/images/ijms-21-01272-g001.png)
IJMS | Free Full-Text | Intrathecal Injection in a Rat Model: A Potential Route to Deliver Human Wharton's Jelly-Derived Mesenchymal Stem Cells into the Brain
![Biodistribution of Adeno-Associated Virus Serotype 5 Viral Vectors Following Intrathecal Injection | Molecular Pharmaceutics Biodistribution of Adeno-Associated Virus Serotype 5 Viral Vectors Following Intrathecal Injection | Molecular Pharmaceutics](https://pubs.acs.org/cms/10.1021/acs.molpharmaceut.1c00252/asset/images/large/mp1c00252_0004.jpeg)
Biodistribution of Adeno-Associated Virus Serotype 5 Viral Vectors Following Intrathecal Injection | Molecular Pharmaceutics
![Biomedicines | Free Full-Text | Intrathecal Injection of the Secretome from ALS Motor Neurons Regulated for miR-124 Expression Prevents Disease Outcomes in SOD1-G93A Mice Biomedicines | Free Full-Text | Intrathecal Injection of the Secretome from ALS Motor Neurons Regulated for miR-124 Expression Prevents Disease Outcomes in SOD1-G93A Mice](https://pub.mdpi-res.com/biomedicines/biomedicines-10-02120/article_deploy/html/images/biomedicines-10-02120-g001.png?1662019988)
Biomedicines | Free Full-Text | Intrathecal Injection of the Secretome from ALS Motor Neurons Regulated for miR-124 Expression Prevents Disease Outcomes in SOD1-G93A Mice
![Targeted intraspinal injections to assess therapies in rodent models of neurological disorders | Nature Protocols Targeted intraspinal injections to assess therapies in rodent models of neurological disorders | Nature Protocols](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41596-018-0095-5/MediaObjects/41596_2018_95_Fig1_HTML.png)
Targeted intraspinal injections to assess therapies in rodent models of neurological disorders | Nature Protocols
![Intrathecal injection procedures. (a) Setup and materials needed for... | Download Scientific Diagram Intrathecal injection procedures. (a) Setup and materials needed for... | Download Scientific Diagram](https://www.researchgate.net/publication/358852631/figure/fig1/AS:1129129038622727@1646216749560/ntrathecal-injection-procedures-a-Setup-and-materials-needed-for-intrathecal.jpg)
Intrathecal injection procedures. (a) Setup and materials needed for... | Download Scientific Diagram
![PKC‐ and PKA‐dependent phosphorylation modulates TREK‐1 function in naïve and neuropathic rats - García - 2021 - Journal of Neurochemistry - Wiley Online Library PKC‐ and PKA‐dependent phosphorylation modulates TREK‐1 function in naïve and neuropathic rats - García - 2021 - Journal of Neurochemistry - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/4556776f-b1e3-4687-aabf-08ef8ea6aa87/jnc15204-fig-0010-m.jpg)
PKC‐ and PKA‐dependent phosphorylation modulates TREK‐1 function in naïve and neuropathic rats - García - 2021 - Journal of Neurochemistry - Wiley Online Library
![Bone-Marrow-Derived Mononuclear Cells Relieve Neuropathic Pain after Spinal Nerve Injury in Mice: Molecular Therapy - Methods & Clinical Development Bone-Marrow-Derived Mononuclear Cells Relieve Neuropathic Pain after Spinal Nerve Injury in Mice: Molecular Therapy - Methods & Clinical Development](https://www.cell.com/cms/asset/419988e2-01bf-48c5-8f51-4a05859f0881/fx1.jpg)
Bone-Marrow-Derived Mononuclear Cells Relieve Neuropathic Pain after Spinal Nerve Injury in Mice: Molecular Therapy - Methods & Clinical Development
![Frontiers | Spinal Cord Molecular and Cellular Changes Induced by Adenoviral Vector- and Cell-Mediated Triple Gene Therapy after Severe Contusion Frontiers | Spinal Cord Molecular and Cellular Changes Induced by Adenoviral Vector- and Cell-Mediated Triple Gene Therapy after Severe Contusion](https://www.frontiersin.org/files/Articles/299318/fphar-08-00813-HTML/image_m/fphar-08-00813-g001.jpg)
Frontiers | Spinal Cord Molecular and Cellular Changes Induced by Adenoviral Vector- and Cell-Mediated Triple Gene Therapy after Severe Contusion
![Neurotoxicity of intrathecal 6% hydroxyethyl starch 130/0.4 injection in a rat model - Vassal - 2015 - Anaesthesia - Wiley Online Library Neurotoxicity of intrathecal 6% hydroxyethyl starch 130/0.4 injection in a rat model - Vassal - 2015 - Anaesthesia - Wiley Online Library](https://associationofanaesthetists-publications.onlinelibrary.wiley.com/cms/asset/2e29ddc8-f182-4989-aa3c-a6e32b9347c3/anae13076-fig-0002-m.jpg)
Neurotoxicity of intrathecal 6% hydroxyethyl starch 130/0.4 injection in a rat model - Vassal - 2015 - Anaesthesia - Wiley Online Library
![Intrathecal injection of manganese chloride. Adapted with permission... | Download Scientific Diagram Intrathecal injection of manganese chloride. Adapted with permission... | Download Scientific Diagram](https://www.researchgate.net/publication/329614013/figure/fig2/AS:703376488689675@1544709431912/Intrathecal-injection-of-manganese-chloride-Adapted-with-permission-from-Liu-et-al.png)
Intrathecal injection of manganese chloride. Adapted with permission... | Download Scientific Diagram
![Distinct transduction profiles in the CNS via three injection routes of AAV9 and the application to generation of a neurodegenerative mouse model: Molecular Therapy - Methods & Clinical Development Distinct transduction profiles in the CNS via three injection routes of AAV9 and the application to generation of a neurodegenerative mouse model: Molecular Therapy - Methods & Clinical Development](https://www.cell.com/cms/attachment/2083461883/2073212701/gr1.jpg)
Distinct transduction profiles in the CNS via three injection routes of AAV9 and the application to generation of a neurodegenerative mouse model: Molecular Therapy - Methods & Clinical Development
![A new minimally-invasive method for microinjection into the mouse spinal dorsal horn | Scientific Reports A new minimally-invasive method for microinjection into the mouse spinal dorsal horn | Scientific Reports](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fsrep14306/MediaObjects/41598_2015_Article_BFsrep14306_Fig1_HTML.jpg)
A new minimally-invasive method for microinjection into the mouse spinal dorsal horn | Scientific Reports
![Intrathecal injection of bone marrow stromal cells attenuates neuropathic pain via inhibition of P2X4R in spinal cord microglia | Journal of Neuroinflammation | Full Text Intrathecal injection of bone marrow stromal cells attenuates neuropathic pain via inhibition of P2X4R in spinal cord microglia | Journal of Neuroinflammation | Full Text](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs12974-019-1631-0/MediaObjects/12974_2019_1631_Fig1_HTML.png)
Intrathecal injection of bone marrow stromal cells attenuates neuropathic pain via inhibition of P2X4R in spinal cord microglia | Journal of Neuroinflammation | Full Text
Spinal cord regional delivery of 7CZ NPs. Mice received 10 µg per 5 µl... | Download Scientific Diagram
![Direct Intrathecal Drug Delivery in Mice for Detecting In Vivo Effects of cGMP on Pain Processing | SpringerLink Direct Intrathecal Drug Delivery in Mice for Detecting In Vivo Effects of cGMP on Pain Processing | SpringerLink](https://media.springernature.com/lw685/springer-static/image/chp%3A10.1007%2F978-1-62703-459-3_14/MediaObjects/300994_1_En_14_Fig2_HTML.jpg)
Direct Intrathecal Drug Delivery in Mice for Detecting In Vivo Effects of cGMP on Pain Processing | SpringerLink
![Intrathecal Administration of Losartan Reduces Directly Recorded Cardiac Sympathetic Nerve Activity in Ovine Heart Failure | Hypertension Intrathecal Administration of Losartan Reduces Directly Recorded Cardiac Sympathetic Nerve Activity in Ovine Heart Failure | Hypertension](https://www.ahajournals.org/cms/asset/22fe3970-0e0a-4ebf-b125-217a980bd27a/896ga1.jpg)
Intrathecal Administration of Losartan Reduces Directly Recorded Cardiac Sympathetic Nerve Activity in Ovine Heart Failure | Hypertension
![JCI Insight - Dynamic dual-isotope molecular imaging elucidates principles for optimizing intrathecal drug delivery JCI Insight - Dynamic dual-isotope molecular imaging elucidates principles for optimizing intrathecal drug delivery](https://df6sxcketz7bb.cloudfront.net/manuscripts/85000/85311/medium/jci.insight.85311.f1.jpg)